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GLP-1 calorie and protein calculator

Your calorie target, your daily protein target and per-meal grams, plus a projection of how much muscle you keep with versus without enough protein and training. Built on published equations, not guesses.

How this is calculated (and the research behind it)

Resting metabolism (BMR). The calculator uses the Mifflin-St Jeor equation, the predictive equation validated as most accurate for healthy adults.1 For women it is 10 × weight(kg) + 6.25 × height(cm) − 5 × age − 161; for men the last term is + 5.

Total burn (TDEE). BMR is multiplied by a physical-activity factor (1.2 sedentary to 1.9 very active), the standard way to scale resting metabolism to real-world expenditure.2 Your calorie target is TDEE minus the deficit implied by your chosen pace.

Weight-loss trajectory. The pace-to-deficit conversion uses the classic estimate that about 7,700 kcal equals one kilogram of body weight (3,500 kcal per pound).3 This is a first approximation. Real loss slows over time as metabolism adapts, so a dynamic model predicts less than a straight line at the far end.4 Treat the timeline as a planning estimate, not a promise.

Protein target. The 1.6 to 2.2 g/kg range comes from lean-mass research, where benefit to fat-free mass leveled off near 1.6 g/kg.5 It is split across four meals because distribution matters more than any single dose.6

Meal timing on a small appetite. The same distribution logic is why the meal planner lets you spread the target across three to five meals: dividing protein into moderate servings through the day supports muscle better than concentrating it in one or two large meals, which is hard to eat anyway when a GLP-1 has cut your hunger.6 On low-appetite days, eat protein first, front-load it earlier when hunger is highest, use liquid sources like a shake or Greek yogurt, and keep the biggest meal away from the peak side-effect window after a dose.

The two muscle lines. Reviews of the trial data put lean mass at roughly 15 to 40 percent of the weight lost on a GLP-1.7 The red line models the higher end that occurs without countermeasures. The green line models the outcome with adequate protein and resistance training, using the finding that resistance training offset about 93.5 percent of the lean mass that caloric restriction alone would cost.8 These are illustrative projections from published ranges, not a measurement of your body.

Honest limits

Every number here is an estimate. Predictive BMR equations carry error at the individual level, the 7,700 kcal rule overstates loss over months, and the muscle split is modeled from population ranges rather than a scan of you. A target scaled to total body weight is a starting point, not a prescription, and it can overestimate protein for people carrying more fat mass. Use this as a framework, and confirm the specifics with your clinician, especially the calorie floor while on a GLP-1.

Frequently asked

How many calories should I eat on a GLP-1?

There is no single right number. The calculator estimates your maintenance calories (TDEE) from your sex, age, height, weight and activity level, then subtracts the deficit that matches the pace you pick, using the classic estimate of 7,700 kcal per kilogram of body weight. Change the pace and the target moves. It is a planning estimate: confirm the calorie floor with your clinician while on a GLP-1.

How does this calculator estimate my calories?

It uses the Mifflin-St Jeor equation for basal metabolic rate (BMR), the most validated predictive equation for healthy adults, then multiplies by a physical-activity factor to estimate total daily energy expenditure (TDEE). Your calorie target is TDEE minus the deficit implied by your chosen pace of weight loss.

How much protein does it recommend, and of what type?

It applies the 1.6 to 2.2 g/kg of body weight range that lean-mass research supports during weight loss, split across four meals. Hit it from complete, leucine-rich sources; collagen is low in leucine and does little for muscle despite the label.

Does the calculator work for women?

Yes. Choose your sex first: the Mifflin-St Jeor equation uses a different constant for women (minus 161) than for men (plus 5), so the calorie target differs. The protein target uses the same 1.6 to 2.2 g/kg range for everyone, scaled to body weight, and it can overestimate protein for people carrying more fat mass.

How should I time meals when a GLP-1 has killed my appetite?

Spread your daily protein across three to five smaller meals rather than one or two large ones, because distributing protein through the day supports muscle better than loading it into a single meal. On a small appetite, eat protein first before other foods, front-load it earlier in the day when hunger is highest, lean on liquid sources like a shake or Greek yogurt on nausea days, and keep your largest meal away from the peak side-effect window after a dose. The calculator's meal planner shows the per-meal grams for the number of meals you choose.

Why does the chart show two muscle lines?

Total weight loss is driven by the calorie deficit and is similar either way. What changes is the composition. Without enough protein and resistance training, a large share of the weight lost is muscle (reviews put lean mass at 15 to 40 percent of GLP-1 weight loss). With adequate protein and resistance training, most of that muscle is spared: a meta-analysis found resistance training offset roughly 93.5 percent of the lean mass that dieting alone would cost. The two lines make that difference visible.

Go deeper

The Protein Playbook

This tool gives you the numbers. The $5 mini-guide gives you the system to hit them: a four-meal method built for a gone appetite, a USDA-sourced food table, and three sample days you can copy.

Get The Protein Playbook — $5 →

Want the training routines and maintenance phase too? The complete $19 handbook covers the rest.

References

  1. Mifflin MD, St Jeor ST, Hill LA, et al. A new predictive equation for resting energy expenditure in healthy individuals. American Journal of Clinical Nutrition. 1990;51(2):241–247. pubmed.ncbi.nlm.nih.gov/2305711
  2. Food and Agriculture Organization / WHO / UNU. Human energy requirements: physical activity level (PAL) values. Report of a Joint Expert Consultation. 2004.
  3. Wishnofsky M. Caloric equivalents of gained or lost weight. American Journal of Clinical Nutrition. 1958;6(5):542–546.
  4. Hall KD, Sacks G, Chandramohan D, et al. Quantification of the effect of energy imbalance on bodyweight. The Lancet. 2011;378(9793):826–837. doi.org/10.1016/S0140-6736(11)60812-X
  5. Morton RW, et al. A systematic review, meta-analysis and meta-regression of the effect of protein supplementation on resistance-training-induced gains. British Journal of Sports Medicine. 2018. pmc.ncbi.nlm.nih.gov/articles/PMC5867436
  6. Schoenfeld BJ, Aragon AA. How much protein can the body use in a single meal for muscle-building? Journal of the International Society of Sports Nutrition. 2018. pmc.ncbi.nlm.nih.gov/articles/PMC5828430
  7. Neeland IJ, et al. Changes in lean body mass with established and emerging GLP-1-based therapies and mitigation strategies. Diabetes, Obesity & Metabolism. 2024. doi.org/10.1111/dom.15728
  8. Sardeli AV, et al. Resistance training prevents muscle loss induced by caloric restriction in obese elderly: a systematic review and meta-analysis. Nutrients. 2018;10(4):423. mdpi.com/2072-6643/10/4/423